Before you can generate a single bill, you need an account. GST-registered businesses register with their GSTIN; unregistered transporters enrol to receive a 15-character Transporter ID (TRANSIN).
Registration for GST taxpayers
On ewaybillgst.gov.in, choose Registration → E-Way Bill Registration, enter your GSTIN and captcha, verify the OTP sent to your registered mobile, and create a username and password. Your business name and address are fetched automatically from your GST registration.
See the detailed registration page and GSTIN registration notes.
Enrolment for transporters
Unregistered transporters use Registration → Enrolment, provide PAN and business details, verify by OTP, and receive a TRANSIN that becomes their login ID. Full detail is on the transporter registration page.
After you register
Log in, register for 2FA (mandatory), confirm your details, and create sub-users for staff if needed. Keep your registered mobile current, since OTPs depend on it.